The other four were killed in airstrikes targeting IS locations in the ancient city of Palmyra in the province of Home.
The report said that the Russian air force carried out 34 missions in al-Karma and Palmyra, where two armories and 12 vehicles were destroyed.
Since September 30, Russia have been targeting IS positions in Syria with aerial bombings, according to Russian and Syrian officials. Opposition activists have condemned the Russian airstrikes claiming they targeted civilians and opposition fighters, not IS terrorists.